SolidSMART : Polymorph, ASD & Salts Screening Software

SolidSMART: Formulation & Screening Software
Accelerate Drug Development with Advanced Screening and Prediction.
SolidSMART is a cutting-edge drug development software designed to transform pharmaceutical research. Utilizing precision-driven algorithms, SolidSMART accelerates formulation and screening processes, delivering actionable insights for pH solubility, salt selection, and polymorph prediction in record time.
Empowering both New Chemical Entities (NCE) and generic pharmaceutical companies, SolidSMART simplifies complex workflows, reducing costs, saving time, and increasing confidence in results. Say goodbye to traditional trial-and-error methods and embrace the future of pharmaceutical innovation with SolidSMART.
- pH Solubility Prediction
- Precision Salt Screening for Enhanced Drug Development
- Transforming XRD Analysis: Effortless Novel Form Discovery

Revolutionary pH Solubility Prediction
Advanced pH Solubility Prediction for Streamlined Formulation Development
SolidSMART delivers precise pH solubility predictions across a broad range (1.2 to 9) in under an hour. Covering 10 key dissolution media, including gastric and intestinal fluids, with 85% accuracy, it provides actionable insights at 10°C, 25°C, and 50°C. This advanced solution accelerates formulation development while ensuring alignment with real-world conditions.
Prolonged Timelines: Traditional pH solubility testing can take up to 14 days per compound, causing delays that extend project timelines by 30%.
Limited Media Coverage: Testing across only 3-5 media types overlooks 70% of real-world conditions, resulting in less effective formulations.
Temperature Variability: Ignoring temperature effects can lead to 20% variations across climates, impacting drug performance.
Rapid Predictions: Solubility data from pH 1.2 to 9 in less than an hour.
Wide Media Coverage: Comprehensive testing across 10 dissolution media types, including gastric and intestinal fluids.
Accurate Buffer Simulations: 85% accuracy across various buffer solutions.
Temperature Flexibility: Solubility assessments at 10°C, 25°C, and 50°C to accommodate different climatic conditions.
For NCEs: Accurate solubility predictions enable stable and effective drug formulations early on, avoiding costly reformulations.
For Generic Drug Companies: Streamlined bioequivalence studies ensure consistency with branded counterparts.
Precision Salt Screening for Enhanced Drug Development
Screen 56 Salt Forms in Just One Hour!
Accelerate your salt screening process with SolidSMART. The software screens Active Pharmaceutical Ingredients (APIs) against 56 salt forms, predicting compatibility and stability across multiple temperatures (10°C, 25°C, 50°C) within one hour. This results in significant time and cost savings while improving your ability to select optimal salt forms for enhanced solubility and stability.
Lengthy Processes: Traditional salt screening can take up to 6 months, delaying drug development.
Suboptimal Evaluation: Limited evaluations miss salts that could significantly enhance drug solubility and stability.
High Costs: Current methods consume 30-40% of R&D budgets, diverting resources from essential tasks.
Rapid Screening: Screen APIs against 56 salt forms within an hour.
Stability Predictions: Evaluate stability at 10°C, 25°C, and 50°C.
High Accuracy: 80% accuracy in predicting newly formed salt solubility in water and gut environments.
Cost Efficiency: Minimize expenses associated with extended screening and manual testing.
For NCEs and Generic Formulations: Quick and precise salt screening supports better salt selection, enhancing drug stability and performance. This facilitates faster market entry and ensures regulatory compliance.
Transforming XRD Analysis: Effortless Novel Form Discovery
Automated XRD Analysis for Unparalleled Accuracy
SolidSMART’s automated XRD analysis tool simplifies novel polymorph identification by analyzing hundreds of files within minutes.
Large Data Volumes: Tedious analysis of 200–500 XRD files per project.
Complex Comparisons: Comparing multiple patented forms is labor-intensive and error-prone.
High Risk of Oversight: Manual efforts increase the chance of missing novel or unique forms.
Time-Consuming Process: Manual analysis can take over 5 days, delaying critical project timelines.
Automated File Processing: Analyze hundreds of XRD files in less than 5 minutes.
High Precision: Accurately detects novel or non-infringing forms, eliminating human errors.
Time Efficiency: Significantly reduces the effort and time required to process large datasets.
Reduced Dependency: Minimizes reliance on manual analysis and IP personnel for data interpretation.
Experience the Future of Drug Development
Transform your drug development pipeline with SolidSMART—a comprehensive solution for pH solubility, salt screening, polymorph prediction, and XRD analysis. Save time, reduce costs, and ensure regulatory compliance with unparalleled precision.
Accelerate your research today with SolidSMART!