SoluDEM - Solubility Prediction Software
SoluDEM : Predict solubility,
Accelerate API Development
SoluDEM is a fast and highly accurate Solubility prediction software designed for API solubility prediction and drug solubility prediction.
This Solvent screening software revolutionizes API R&D by allowing scientists to screen thousands of solvents in hours, eliminate experimental guesswork, and accelerate development timelines. As a predictive, data-driven API development software, SoluDEM supports smarter solvent selection and robust process design right from early development.
Built using thermodynamic principles combined with predictive data, SoluDEM delivers predictive solubility modelling to support reaction design, crystallization, and formulation workflows. It empowers R&D teams to move faster, reduce risk, and improve outcomes across API development, crystallization, and pharmaceutical process development.
Industry Challenges
- 60–70% of early development time is spent on solvent and crystallization screening.
- Typical projects evaluate less than 5% of the feasible solvents, and avoids the larger scientific space due to experimental limitations.
- 40% of projects face low-yield challenges, due to poor solubility behaviour.
- 60% of projects struggle with impurity removal, leading to development delays.
Key Capabilities of SoluDEM
Massive Solvent Screening
Perform large-scale virtual solvent screening, capable of evaluating up to 11,000 solvent systems, including:
- Pure solvents
- Binary solvent systems
- Custom ternary solvent combinations
All predictions are delivered within 8–12 hours, significantly faster than traditional experimental approaches.
Multi-Temperature Solubility Prediction
Enable accurate drug solubility prediction and API solubility prediction at:
- 10°C
- 25°C
- 50°C
These conditions are designed to reflect real-world pharmaceutical process and formulation environments.
ICH-Approved Solvent Coverage
SoluDEM supports ICH Q3C-compliant solvent selection, enabling regulatory-aligned pharmaceutical solubility prediction and solvent screening for safe and compliant development.
Wide Compound Applicability
SoluDEM pharmaceutical R&D software is applicable to:
- APIs
- Impurities
- Intermediates
- Starting materials
No experimental solubility data required
Yield Improvement Prediction
Using predictive solubility modelling, SoluDEM identifies solvent systems that:
- Improve yield with lower volume
- Reduce material loss
- Enhance overall pharmaceutical process efficiency
Impurity Rejection
SoluDEM enables solvent strategies that:
- Improve impurity rejection
- Enhance crystallization selectivity
Why Choose SoluDEM Over Traditional Screening?
Traditional Approach | SoluDEM |
Trial-and-error experiments | Predictive, data-driven |
Weeks to months | Results in hours |
High material consumption | Zero experimental input |
Limited solvent coverage | 11,000+ solvents |
Late-stage failures | Early-stage confidence |
Transform Solubility Challenges into Competitive Advantage
With SoluDEM, organizations can:
- Shorten development timelines
- Reduce solvent screening costs
- Improve yield and purity
- Make confident early-stage decisions
- Strengthen pharmaceutical process robustness
Discover how SoluDEM can transforms your development activities with predictive solubility modelling, API solubility prediction, and next-generation pharmaceutical R&D software.
