Frequently Asked Questions
Find answers to common questions about PharmaDEM and our AI-powered solutions for pharmaceutical development.
Select a category above to view FAQs.
About PharmaDEM 🧬
Which business PharmaDEM is into?
PharmaDEM is into techno-chemistry platform designed to support pharmaceutical companies in API process development, Formulation development, Formulation optimization, and digital transformation and integration to Pharmaceutical R&D.
Who can benefit from PharmaDEM?
Organizations which are into API manufacturing Pharmaceutical R&D (Formulations & API) teams, and process development scientists looking to improve efficiency, reduce costs, and enhance product quality.
What makes PharmaDEM stand unique?
PharmaDEM combines scientific expertise with digital innovation. It brings deep chemistry blended with digital expertise which comprehensively addresses the pharmaceutical industry on issues like purity, yield optimization, impurity control, and cost reduction—all in one platform.
What products are PharmaDEM products?
The primary products of PharmaDEM which offers specialized solutions are SoluDEM, SolidSMART, FormSCI, and eLabNote. Each one is designed to address specific challenges in pharmaceutical research and development.
How does PharmaDEM help improve API processes?
PharmaDEM uses advanced analytics and AI-driven approaches to identify process inefficiencies, optimize reactions, and improve overall product quality while minimizing costs and impurities.
Is PharmaDEM products & solutions are suitable for small and large companies?
Yes, PharmaDEM solutions are scalable and can be tailored to meet the needs of both small research teams and large pharmaceutical enterprises.
Does PharmaDEM provide customized solutions?
Yes, PharmaDEM offers custom solutions based on specific project requirements and business goals.
How can I learn more about PharmaDEM products?
You can explore individual product pages, request a demo, or contact our team for detailed insights on how PharmaDEM can support your operations.
FormSCI 🔬
Is FormSCI useful for complex injectable formulations?
Yes. FormSCI is suitable for injectables as well as all other types of dosage forms, including complex formulations.
What type of data is used to train the AI model?
The AI model is pre-trained using thousands of experimental datasets. Users are not required to provide any experimental data for performing predictions or calculations. The software accepts inputs of API properties, and excipient weight fractions, temperature & RH conditions, and polymorph-specific information.
Does the stability prediction include both chemical and polymorphic stability
Yes. FormSCI predicts both chemical stability, and polymorphic form stability. The predictions are based on key parameters such as heat of fusion (ΔHfus) and melting point (MP) data.
What is the accuracy of prediction?
FormSCI predict with ~80% accuracy. Industry’s feedback is has even better accuracy.
Can FormSCI differentiate between varios grades of the same excipient?
Yes, software can evaluate grade specific excipients.
Does FormSCI consider packaging materials such as blisters or HDPE bottles?
Yes. FormSCI has capability to screen and evaluate the impact of approximately 20 different packaging materials on formulations.
Can we evaluate stability with respect to nitrosamine impurities?
Yes. FormSCI can perform impurity root cause analysis for both known and unknown impurities.
Is FormSCI a regulatory tool?
FormSCI is not a replacement for regulatory tools. It is designed for operational excellence, helping in formulation R&D to accelerate formulation design activities, and optimization of formulations
SoluDEM ⚗️
What is SoluDEM?
SoluDEM is advanced Solubility Prediction software designed to predict solubility, specifically tailored for API development. It utilizes powerful algorithms to assess solubility across a 11,000+ of solvents, aiding in API Development, formulation optimization and process efficiency.
How accurate is SoluDEM in predicting solubility?
SoluDEM stands at ~85% of accuracy. It is validated across various chemical types and conditions. This reliability helps minimize experimental guesswork and accelerates R&D timelines.
What types of solvents can SoluDEM screen?
SoluDEM can screen up to 11,000 solvents, including pure, binary, and custom ternary combinations. It covers all ICH-approved solvents, ensuring comprehensive suitability for diverse chemical applications.
What applications does SoluDEM support?
SoluDEM is suitable for APIs, impurities, starting materials, and various chemical entities without the need for prior experimental data. It aids in improving yield, optimizing drug formulations, and enhancing the efficiency of pharmaceutical and chemical processes.
Does SoluDEM require extensive training to use?
SoluDEM is designed with user convenience in mind which typically requires minimal training to use effectively. Support and documentation are provided to assist users to best utilize for solubility prediction and process optimization
What factors does SoluDEM consider when predicting potential yield improvements?
SoluDEM considers solvent-solute interactions, temperature variations (10°C, 25°C, 50°C), and the impact of solvent composition on solubility to recommend conditions conducive to higher yield.
Can SoluDEM provide recommendations for optimizing conditions to maximize yield
Yes, SoluDEM provides insights into solvent selection and temperature adjustments that can optimize conditions for maximum yield during chemical reactions and formulation processes.
Can SoluDEM predict solubility differences that impact impurity rejection?
Yes, SoluDEM predicts solubility at multiple temperatures providing insights of solvents that minimize impurity solubility while maximizing API solubility.
eLabNote📓
What is eLabNote and why does your lab need it?
eLabNote is a secure, cloud-based Electronic Lab Notebook (eLN) designed for pharmaceutical, biotech, CRO, academic, and industrial laboratories — helping scientists for digitization of experiment details, and avoiding paperwork.
How is eLabNote different from a traditional paper lab notebook?
Unlike paper notebooks, eLabNote enables structured and unstructured data capture, secure tamper-proof electronic records, full audit trails, electronic signatures, and easy collaboration across labs and locations.
Is eLabNote ready to deploy or does it need heavy customization?
Ready when you are. eLabNote 90% pre-built and 10% in intentionally left for customization of respective client needs. It is100% configurable. ready-to-deployin less than 30 days.
Does eLabNote meet global pharma regulatory compliance standards?
Absolutely. eLabNote is FDA 21 CFR Part 11 compliant and supports GxP (GLP, GMP) and ISO standards, with role-based access control, tamper-proof audit trails with timestamps, and electronic signatures with non-repudiation.
What kind of data can scientists capture in eLabNote?
Everything your lab generates. eLabNote supports drag-and-drop file uploads including PDFs, images, spectra, and reports, and manages both structured and unstructured lab data — all in one place.
How much time can eLabNote actually save my team?
Significantly. eLabNote reduces lab data entry time by up to 60%, enables faster data retrieval and reporting, and lowers compliance and audit preparation costs — freeing your team for higher-value work.
Is eLabNote AI-ready and future-proof for digital transformation?
Yes. eLabNote fully supports FAIR data principles — making lab data traceable, Accessible, Interoperable, and Reusable — ensuring it is future-proof, AI-ready, and reusable across projects.
How is eLabNote deployed and what support does PharmaDEM provide?
Flexible and fully supported. eLabNote is available as a cloud-based or on-premise solution with no local software installation required. PharmaDEM provides end-to-end implementation, rapid onboarding, lab-specific workflow configuration, and ongoing customer support.
SolidSMART 🧪
What makes SolidSMART a game-changer in pharmaceutical drug development?
SolidSMART is an AI-driven solid state chemistry software that replaces, trial-and-error lab work with precision algorithms, by delivering instant insights for pH solubility, salt selection, polymorph prediction, and ASD polymer screening, all at one platform.
How does SolidSMART help with pH solubility prediction?
SolidSMART predicts solubility across pH 1.2 to 9, covering 10 dissolution media — including gastric and intestinal fluids — with 85% accuracy. What used to take 14 days now takes less than 60 minutes.
How many salt forms does SolidSMART screen — and how quickly?
SolidSMART screens your API against 56 FDA-approved salt forms in just one hour, with stability predictions at 10°C, 25°C, and 50°C. Traditional methods may take up to 6 months. The choice is clear.
What accuracy can I expect from SolidSMART's salt solubility predictions?
SolidSMART delivers 80% accuracy in predicting newly formed salt solubility in both water and gut environments — giving your team the highest confidence to select the choice of appropriate salt form at first go.
How does SolidSMART revolutionize polymorph screening?
It screens APIs across 11,000 solvent systems in multiple combinations, at temperatures from 10°C to 50°C, predicting new solid form formation from molecular structures — cutting down weeks of manual lab work to just hours.
Does SolidSMART automate XRD data analysis too?
Yes! SolidSMART processes hundreds of XRD files in 5 minutes, automatically detecting novel or non-infringing polymorphic forms — eliminating human error
What is ASD polymer screening and how does SolidSMART simplify it?
SolidSMART evaluates 34 polymers for API compatibility across multiple temperatures and weight fractions — predicting miscibility, stability, and gut solubility for better amorphous solid dispersions, faster.
Who can benefit from SolidSMART?
SolidSMART empowers both New Chemical Entity (NCE) developers and generic pharmaceutical companies by simplifying complex workflows, reducing costs, saving time, and increasing confidence in results. It is suitable for formulation scientists, Pre-formulation teams, and API R&D departments.
Support 🖥️
How can I contact PharmaDEM support?
You can reach our support team through the contact form on our website or by emailing us directly. Our team is ready to assist you with any queries.
What kind of support does PharmaDEM provide?
We provide technical support, product guidance, onboarding assistance, and troubleshooting to ensure you get the best experience from our solutions.
Is onboarding support available for new users?
Yes, we offer guided onboarding to help new users understand and effectively use our platform and products.
How quickly can I expect a response from support?
Our team aims to respond within 24–48 hours, depending on the complexity of the query.
Where Can I request a demo?
You can request a demo through our website to better understand how our solutions fit your needs.
Do you provide training for your products?
Yes, we offer training sessions and documentation to help users maximize the value of our solutions.
What should I do if I face a technical issue?
If you encounter any issues, please contact our support team with details, and we will assist you in resolving it as quickly as possible.
Is ongoing support available after implementation?
Yes, we provide continuous support even after implementation to ensure smooth operations and long-term success.